Folder Redirection - Redirect all folders such as My Documents, Downloads, App Data etc to a network share to ensure that this data does not get saved locally. This is best practise for disaster recovery and backup as well as VDI / Hosted Desktops do not get backed up.
Disable C Drive Access - To force users to save data to network shares its recommended to hide the C drive through a Group Policy
Disable local cached mode for Outlook - Ensure that Outlook either runs in Online mode or has its cached files redirected to a network share.
Regular Temp Files Cleaning - Ensure windows temporary are cleaned regularly, ideally on a schedule.